pentobarbital will minimize the level or impact of exemestane by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. For clients acquiring exemestane with a strong CYP3A4 inducer the encouraged dose of exemestane is 50 mg day-to-day following a food.
pentobarbital will decrease the level or effect of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Keep an eye on patients by now on buprenorphine subdermal implant who need recently-initiated therapy with CYP3A4 inducer for symptoms and signs or symptoms of withdrawal.
pentobarbital will minimize the level or outcome of clarithromycin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
pentobarbital will decrease the level or outcome of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Strong CYP3A4 inducers are anticipated to trigger sizeable decreases in sildenafil plasma concentrations
pentobarbital will lower the extent or result of bedaquiline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Steer clear of coadministration of bedaquiline with powerful CYP3A4 inducers resulting from potential for reduced therapeutic result
pentobarbital will minimize the extent or result of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. The efficacy of hormonal contraceptives could be lessened. Utilization of a nonhormonal contraceptive is recommended.
pentobarbital will lessen the extent or effect of elagolix by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will minimize the extent or result of maraviroc by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the level or effect of colchicine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
This drug might interfere with the absorption of orally administered griseofulvin, reducing its blood concentrations; effects of blood degree reduction mysterious; preferable to avoid concomitant administration of these drugs
Contraindicated (one)pentobarbital will minimize the extent or result of lorlatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or influence of tramadol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Decreased AUC of tramadol as well as Energetic metabolite (O-desmethyltramadol) when coadministered with robust CYP3A4 and CYP2B6 inducers
pentobarbital will reduce the level or outcome of diazepam by influencing more info hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Reserve concomitant prescribing of such drugs in patients for whom other cure options are inadequate. Restrict dosages and durations to the bare minimum expected. Observe carefully for signs of respiratory melancholy and sedation.